G patch domain and kow motif-containing protein drinks

Gpkows ability to bind rna is regulated by pkadependent phosphorylation at two sites. Gpkow gpatch domain and kow motifscontaining protein. The short motifs lying on the distal ends of the disordered linkers are. The major human spliceosome contains 45 distinct proteins in its snrnp. In eukaryotes, the remainder of the central region between the ngn and the ctr contains five kow motifcontaining domains.

An example hereof is the processing of the gpatch domainand kow motif containing t54 protein. Kow motif of the g patch domain and kow motifscontaining protein gpkow repeat b gpkow contains one g patch domain and two kow motifs. Sugp1 surp and gpatch domaincontaining protein 1 homo. Arabidopsis vq motifcontaining proteins vq12 and vq29. Mos2, a protein containing gpatch and kow motifs, is essential for. Diseases associated with gpatch2 include lymphogranuloma venereum and granuloma inguinale. Loc102890286 g patch domain and kow motifscontaining protein black flying fox gene id. We have demonstrated that gpkow binds rna in vivo and that gpkow associate with c. Structures and functions of the multiple kow domains of.

Arabidopsis snc1 encodes a tirnbslrrtype r protein with a similar structure to nucleotide binding oligomerization domain nod proteins in animals. Structural bioinformatics of the human spliceosomal proteome. Gpatch2 gene genecards gptc2 protein gptc2 antibody. Gpatch domain and kow motifscontaining protein, gpkow ncbi. Gpatch domain and kow motifscontaining protein, gpkow. Gene ontology go annotations related to this gene include nucleic acid binding. Deletions of intronic region containing m6alinked drach motif resulted in partial diminution of. Gpkow is a nuclear protein that regulated by catalytic c subunit of protein kinase a pka and bind rna in vivo. Identification of droughtresponsive universal stress proteins in viridiplantae article pdf available in bioinformatics and biology insights 55. In contrast, the archaeal and bacterial proteins contain only a single cterminal kow domain without a ctrlike tail see fig. The biology of rnaprotein complexes universitat regensburg. Arabidopsis vq motifcontaining proteins have recently been demonstrated to interact with several wrky transcription factors. Using yeast twohybrid screening with the pka c subunit cbeta2 as bait, we identified the gpatch domain and kow motifscontaining protein.

Gpatch11 is a protein that in humans is encoded by the g patch domain containing protein 11 gene. Gpkow is a nuclear protein with three nucleic acid binding domains, one gpatch domain and two kowmotifs. Gpatch2 g patch domain containing 2 is a protein coding gene. Gpatch domain ipr000467 interpro entry interpro emblebi. The protein has been found to interact with several other proteins, including two from a splicing pathway. Loc102890286 g patch domain and kow motifscontaining. The gene has four transcript variants encoding two functional protein isoforms and is expressed in most human tissues. An evolutionarily structured universe of protein architecture. Using yeast twohybrid screening with the pka c subunit cbeta2 as bait, we identified the gpatch domain and kow motifscontaining protein gpkow, also known as the t54 protein or mos2 homolog, as an interaction partner for cbeta2.